(S,S)-Oxaliplatin

CAS : 61758-77-8

Ref. TR-O845080

Informations sur le produit

• Nom: (S,S)-Oxaliplatin
• Synonymes: Platinum, [(1S,2S)-1,2-cyclohexanediamine-kappaN1,kappaN2][ethanedioato(2-)-kappaO1,kappaO2]-, (SP-4-2)-, Platinum, (1,2-cyclohexanediamine-kappaN,kappaN')[ethanedioato(2-)-kappaO1,kappaO2]-, [SP-4-2-[1S-(trans)]]-, Platinum, [(1S,2S)-1,2-cyclohexanediamine-kappaN,kappaN'][ethanedioato(2-)-kappaO1,kappaO2]- (9CI), 1,2-Cyclohexanediamine, platinum complex, (1S-trans)-, [(1S,2S)-1,2-Cyclohexanediamine-kappaN1,kappaN2][ethanedioato(2-)-kappaO1,kappaO2]platinum, NSC 266042, Platinum, (1,2-cyclohexanediamine-N,N')[ethanedioato(2-)-O,O']-, [SP-4-2-(1S-trans)]-, (SP-4-2)-[(1S,2S)-Cyclohexane-1,2-diamine-kappaN,kappaN′][ethanedioato(2-)-kappaO1,kappaO2]platinum, Oxaliplatin Imp. D (EP)
• Marque: TRC
• Description: Applications The (S,S) Oxaliplatin isomer. Third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.References Kidani, Y., et al.: J. Med. Chem., 21, 1315 (1978), Kizu, R., et al.: Cancer Chemother. Pharmacol., 31, 475 (1993), Levi, F., et al.: Eur. J. Cancer, 29A, 1280 (1993), Simpson, D., et al.: Drugs, 63, 2127 (2003),

Propriétés chimiques

• Masse moléculaire: 397.29
• Formule: C₈H₁₄N₂O₄Pt
• Couleur/Forme: White
• InChI: InChI=1S/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-6H,1-4,7-8H2;(H,3,4)(H,5,6);/q;;+2/p-2/t5-,6-;;/m0../s1
• Code InChI: InChIKey=ZROHGHOFXNOHSO-USPAICOZSA-L