Paclitaxel-13C6

CAS : 33069-62-4

Ref. TR-P132504

Informations sur le produit

• Nom: Paclitaxel-13C6
• Synonymes: Abraxane-13C6, Genaxol-13C6, Genetaxyl-13C6, OncoGel-13C6, Onxal-13C6, Pacliex-13C6, Taxol-13C6, Yewtaxan-13C6, NSC 125973-13C6, 5β,20-Epoxy-1,2a,4,7β,10β,13α-hexahydroxy-tax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine, 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv., 7,11-Methano-5H-Cyclodeca[3,4]Benz[1,2-B]Oxete Benzenepropanoic Acid Deriv., Abi 007, Abraxane, Anzatax, Apealea, Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-, Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-, Bms 181339-01, Capxol, Coroflex Please, Cremophor-free paclitaxel, Cyclopax, Cynviloq, Cypher select, Dhp 107, Ebetaxel, EmPAC, EndoTAG 1, Genaxol, Genetaxyl, Genexol, Genexol-PM, Ig 001, Ig 002, Infinnium, Intaxel, Lep-Etu, Liposome-entrapped paclitaxel easy-to-use, Mbt 0206, Mitotax, Nab-paclitaxel, Nanotax, Nanoxel, Nk 105, Nsc 125973, OncoGel, Onxal, Oraxol, Pacitaxel, Pacliex, Padexol, Paxene, Pazenir, Plaxicel, Qw 8184, Sindaxel, TAXUS Express, TAXUS stent, Tax-11-en-9-one, 5β,20-epoxy-1,2α,4,7β,10β,13α-hexahydroxy-, 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine, TaxAlbin, Taxal, Taxol, Taxol A, Taxus, Taxus Liberte, Tocosol Paclitaxel, Yewtaxan

Description

Applications Paclitaxel-13C is the labeled analogue of Paclitaxel (P132500). Paclitaxel is an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.
References Letourneau, P.C., et al.: J. Cell Biol., 98, 1355 (1984), Manfredi, J.J., et al.: Pharmacol. Ther., 25, 83 (1984), Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1995), Markman, M., et al.: Expert. Opin. Pharmacother., 3, 755 (2002), Stone, G.W., et al.: N. Engl. J. Med., 350, 221 (2004),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 859.86
• Formule: C₄₁₁₃C₆H₅₁NO₁₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35+,36-,37+,38+,40-,45+,46-,47+/m0/s1/i9+1,14+1,15+1,20+1,21+1,30+1
• Code InChI: InChIKey=RCINICONZNJXQF-IEMAKSHKSA-N
• SMILES: CC(=O)O[C@H]1C(=O)[C@]2(C)[C@@H](O)C[C@H]3OC[C@@]3(OC(C)=O)[C@@H]2[C@H](OC(=O)[13c]2[13cH][13cH][13cH][13cH][13cH]2)[C@]2(O)C[C@H](OC(=O)[C@@H](O)[C@H](NC(=O)c3ccccc3)c3ccccc3)C(C)=C1C2(C)C