Palbociclib Sulfate Sodium Salt

CAS : 571190-30-2

Ref. TR-P139905

Informations sur le produit

• Nom: Palbociclib Sulfate Sodium Salt
• Synonymes: 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(1-piperazinyl)-2-pyridinyl)amino)pyrido[2,3-d]pyridin-7(8H)-one, 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one, 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one, 6-acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-ylpyridin-2-ylamino)-8H-pyrido(2,3-d)pyrimidin-7-one, Ibrance, Otava-Bb 1115529, Palbociclib, Palbociclib base, Palbocyclib, Pd 332991, Pd 991, Pd-0332991, Pd0332991, Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-
• CAS: 571190-30-2

Description

Applications Palbociclib Sulfate is a derivative of Palbociclib (P139900) which is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
References Finn, R., et al.: Breast Cancer Res., 11, 5 (2009)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 549.58
• Formule: C₂₄H₂₈N₇NaO₅S
• Couleur/Forme: Neat
• InChI: InChI=1S/C24H29N7O5S.Na/c1-15-19-14-26-24(28-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32)27-20-8-7-18(13-25-20)29-9-11-30(12-10-29)37(34,35)36;/h7-8,13-14,17H,3-6,9-12H2,1-2H3,(H,34,35,36)(H,25,26,27,28);/q;+1/p-1
• Code InChI: InChIKey=IDXHLGTUYXGQEK-UHFFFAOYSA-M
• SMILES: CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCN(S(=O)(=O)O[Na])CC4)cn3)nc2n(C2CCCC2)c1=O