Palbociclib-d4 Hydrochloride

CAS : 571190-30-2

Ref. TR-P139937

Informations sur le produit

• Nom: Palbociclib-d4 Hydrochloride
• Synonymes: 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one-d4 Hydrochloride, 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one-d4 Hydrochloride, Ibrance-d4 Hydrochloride, PD 0332991-d4 Hydrochloride, PD 332991-d4 Hydrochloride, PD 991-d4 Hydrochloride, 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(1-piperazinyl)-2-pyridinyl)amino)pyrido[2,3-d]pyridin-7(8H)-one, 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one, 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one, 6-acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-ylpyridin-2-ylamino)-8H-pyrido(2,3-d)pyrimidin-7-one, Ibrance, Otava-Bb 1115529, Palbociclib, Palbociclib base, Palbocyclib, Pd 332991, Pd 991, Pd-0332991, Pd0332991, Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-

Description

Applications Palbociclib-d4 Hydrochloride is an intermediate in synthesizing Palbociclib-d4 (P139901), an isotope labelled compound of Palbociclib (P139900). Palbociclib (P139900) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
References Finn, R., et al.: Breast Cancer Res., 11, 5 (2009)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 465.58 + (36.46)
• Formule: C₂₅H₂₇D₄N₇O₂·HCl
• Couleur/Forme: Neat
• SMILES: CS(=O)(=O)NC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]