Pazopanib-d3 Hydrochloride

CAS : 635702-64-6

Ref. TR-P210927

Informations sur le produit

• Nom: Pazopanib-d3 Hydrochloride
• Synonymes: Votrient-d3 Hydrochloride, 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide-d3 Hydrochloride, 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)methylamino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide monohydrochloride, 5-(4-((2,3-dimethyl-2H-indazol-6-yl)(Methyl)amino)pyrimidin-2-ylamino)-2-Methylbenzenesulfonamide hydrochloride, 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide hydrochloride, Benzenesulfonamide, 5-((4-((2,3-dimethyl-2H-indazol-6-yl)methylamino)-2-pyrimidinyl)amino)-2-methyl-,monohydrochloride, Benzenesulfonamide, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-, hydrochloride (1:1), Gw 786034B, Gw786034B, Pazopanib HCl, Unii-33Y9Anm545, Votrient

Description

Applications Pazopanib-d3 is the isotope labelled analog of Pazopanib (P210925), an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
References Olaussen, K., et al.: Oncogen., 28, 4249 (2009), Sleijfer, S., et al.: J. Clin. Oncol., 27, 3126 (2009), Chan, A., et al.: Drugs, 69, 167 (2009),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 477.0
• Formule: C₂₁H₂₁D₃ClN₇O₂S
• Couleur/Forme: Neat
• InChI: InChI=1S/C21H23N7O2S.ClH/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16;/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25);1H/i3D3
• Code InChI: InChIKey=MQHIQUBXFFAOMK-FJCVKDQNSA-N
• SMILES: Cl.[2H]C([2H])([2H])N(c1ccc2c(C)n(C)nc2c1)c1ccnc(Nc2ccc(C)c(S(N)(=O)=O)c2)n1