PBS 57

CAS : 898531-99-2

Ref. TR-P215300

Informations sur le produit

• Nom: PBS 57
• Synonymes: (15Z)-N-[(1S,2S,3R)-1-[[[6-(Acetylamino)-6-deoxy-α-D-galactopyranosyl]oxy]methyl]-2,3-dihydroxyheptadecyl]-15-tetracosenamide

Description

Applications A galactosylceramide derivative used in the treatment of influenza. PBS-57 has the ability to stimulate both a cell-mediated and humoral immune response. Co-administration of PBS-57 with a vaccine may be used in methods to stimulate one or more of a humoral immune response, a CD4+ T cell response, and a CD8+ cytotoxic T cell response.
References Liu, Y., et al.: J. Immunol. Methods, 312, 34 (2006), Kamijuku, H., et al.: Mucosal Immunology, 1, 208 (2008), Kopecky-Bromberg, S; Vaccine, 27, 3766 (2009),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 869.305
• Formule: C₅₀H₉₆N₂O₉
• Couleur/Forme: Neat
• InChI: InChI=1S/C50H96N2O9/c1-4-6-8-10-12-14-16-18-19-20-21-22-23-24-25-26-28-30-32-34-36-38-45(55)52-42(40-60-50-49(59)48(58)47(57)44(61-50)39-51-41(3)53)46(56)43(54)37-35-33-31-29-27-17-15-13-11-9-7-5-2/h18-19,42-44,46-50,54,56-59H,4-17,20-40H2,1-3H3,(H,51,53)(H,52,55)/b19-18-/t42?,43-,44?,46+,47+,48+,49?,50+/m1/s1
• Code InChI: InChIKey=LIXVHWQNKBIZBR-IZJXYXLGSA-N
• SMILES: CCCCCCCC/C=C\CCCCCCCCCCCCCC(=O)NC(CO[C@H]1OC(CNC(C)=O)[C@H](O)[C@H](O)C1O)[C@H](O)[C@H](O)CCCCCCCCCCCCCC