Perindopril t-Butylamine Salt

CAS : 107133-36-8

Ref. TR-P287505

Informations sur le produit

• Nom: Perindopril t-Butylamine Salt
• Synonymes: Perindopril tert-butylamine, 2-Methylpropan-2-amine (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]propanoyl]octahydro-1H-indole-2-carboxylate, 2-Methyl-2-propanamine (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylate, Aceon, Butylaminiperindopril, Conversyl, Coversum, Coversyl, McN-A 2833-109, Perigard, Perindopril erbumine, Perindopril tert-butylamine salt, Perindopril-tert-butylamine, Perinodopril, Perinodpril erbimune, Prestarium, Procaptan, S 9490-3, [2S-[1[R*(R*)],2alpha,3abeta,7abeta]]-1-[2-[[1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid compd. with 2-methyl-2-propanamine (1:1), 2-Methyl-2-propanamine [2S-[1[R*(R*)],2alpha,3abeta,7abeta]]-1-[2-[[1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylate, Perindoprilerbumine, (2S,3aS,7aS)-1-{(2S)-2-[(1-ethoxy-1-oxopentan-2-yl)amino]propanoyl}octahydro-1H-indole-2-carboxylic acid - 2-methylpropan-2-amine (1:1) (non-preferred name), 2-Propanamine, 2-methyl-, (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylate, (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methylpropan-2-amine (1:1) (non-preferred name), (2S,3aS,7aS)-1-[(2R)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methylpropan-2-amine (1:1) (non-preferred name), 1H-Indole-2-carboxylic acid, 1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-, (2S,3aS,7aS)-, compd. with 2-methyl-2-propanamine (1:1), 1H-Indole-2-carboxylic acid, 1-[2-[[1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-, [2S-[1[R*(R*)],2α,3aβ,7aβ]]-, compd. with 2-methyl-2-propanamine (1:1), 1-[2-(1-Ethoxycarbonylbutylamino)propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid 2-methyl-2-propanamine (1:1), (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid (non-preferred name), Perindopril Tert-Butylamine, (2S,3aS,7aS)-1-[(2R)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid (non-preferred name), 2-Propanamine, 2-methyl-, [2S-[1[R*(R*)],2α,3aβ,7aβ]]-1-[2-[[1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylate

Description

Applications An angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.
References Lees, K.R., et al.: Brit. J. Clin. Pharmacol., 23, 159 (1987), Morgan, T., et al.: J. Cardiovasc. Pharmacol., 10, Supp. 7, S116, (1987)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 441.60
• Formule: C₁₉H₃₂N₂O₅·C₄H₁₁N
• Couleur/Forme: Off-White
• InChI: 5H2,1-3H3/t12-,13-,14-,15-,16-, /m0./s1, 1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24), InChI=1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24
• Code InChI: InChIKey=IYNMDWMQHSMDDE-MHXJNQAMSA-N
• SMILES: CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@@H]2CCCC[C@@H]21)C(=O)OCC