1-Phenyl-pyrazole 4-pyruvic Acid

CAS : 1052567-31-3

Ref. TR-P336440

Informations sur le produit

• Nom: 1-Phenyl-pyrazole 4-pyruvic Acid
• Synonymes: 2-oxo-3-(1-phenylpyrazol-4-yl)propanoic acid

Description

Applications 1-Phenyl-pyrazole 4-pyruvic Acid is a derivative of N-Phenylpyrazole, a reactant in the synthesis of candesartan cilexetil(C175580), an ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive.
References Seki, M. et. al: ACS Catalysis, 4, 4047 (2014); Shibouta, Y., et al.: J. Pharmacol. Exp. Ther., 266, 114 (1993; Ogihara, T., et al.: Clin. Ther., 16, 74 (1994)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 230.219
• Formule: C₁₂H₁₀N₂O₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C12H10N2O3/c15-11(12(16)17)6-9-7-13-14(8-9)10-4-2-1-3-5-10/h1-5,7-8H,6H2,(H,16,17)
• Code InChI: InChIKey=DRPATNHCBBZMLW-UHFFFAOYSA-N
• SMILES: O=C(O)C(=O)Cc1cnn(-c2ccccc2)c1