PIK-75

CAS : 372196-67-3

Ref. TR-P437670

Informations sur le produit

• Nom: PIK-75
• Synonymes: 2-Methyl-5-nitro-benzenesulfonic Acid [(6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene]methylhydrazide, Benzenesulfonicacid, 2-methyl-5-nitro-, [(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]methylhydrazide(9CI), Pik 75, N'-[(1Z)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylidene]-N,2-dimethyl-5-nitrobenzenesulfonohydrazide, Benzenesulfonic acid, 2-methyl-5-nitro-, [(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]methylhydrazide
• CAS: 372196-67-3

Description

Applications PIK-75 is a p110α inhibitor, isoform-specific mutants at Ser773, and also potently inhibits DNA-PK.
References Zheng, Z., et al.: Mol. Pharmacol., 80, 657 (2011); Moir, L., et al.: J. Pharmacol. Exp. Ther., 337, 557 (2011); Jude, J., et al.: Am. J. Respir. Cell. Mol. Biol., 65, 2011

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 452.28
• Formule: C₁₆H₁₄BrN₅O₄S
• Couleur/Forme: Neat
• InChI: InChI=1S/C13H15N5O3S2/c1-17(2)23(19,20)11-4-3-10(12-13(11)16-21-15-12)18-6-5-9(7-18)14-8-22/h3-4,9H,5-7H2,1-2H3/t9-/m0/s1
• Code InChI: InChIKey=YMXYIIXTKUQWPC-VIFPVBQESA-N
• SMILES: CN(C)S(=O)(=O)c1ccc(N2CC[C@H](N=C=S)C2)c2nonc12