(R)-Pinocembrin

CAS : 206660-42-6

Ref. TR-P468505

Informations sur le produit

• Nom: (R)-Pinocembrin
• Synonymes: (2R)-2,3-Dihydro-5,7-dihydroxy-2-phenyl-4H-1-benzopyran-4-one, (R)-2,3-dihydro-5,7-dihydroxy-2-phenyl-4H-1-benzopyran-4-one, (-)-Pinocembrin, (-)-Pinocoembrin

Description

Applications (2R)-Pinocembrin is the (R)-enantiomer of Pinocembrin, a flavanoid with antioxidant activity found in damiana, honey, and propolis. (2R)-Pinocembrin is a potential inhibitor of PIM1 kinase, an oncogene that has been implicated in the development of leukemias, lymphomas, and prostate cancer.
References Zhao, J. et al.: J. Ethnopharmacol., 120, 387 (2008); Holder, S. et al.: Mol. Cancer Ther., 6, 163 (2007); Holder, S. et al.: Bioorg. Med. Chem., 15, 6463 (2007);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 256.25
• Formule: C₁₅H₁₂O₄
• Couleur/Forme: White
• InChI: InChI=1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2/t13-/m1/s1
• Code InChI: InChIKey=URFCJEUYXNAHFI-CYBMUJFWSA-N
• SMILES: O=C1C[C@H](c2ccccc2)Oc2cc(O)cc(O)c21