(S)-Pramipexole

CAS : 104632-26-0

Ref. TR-P700750

Informations sur le produit

• Nom: (S)-Pramipexole
• Synonymes: 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, (6S)-, 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, (S)-, (-)-Pramipexole, (S)-2-Amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole, Mirapexin, Pramipexole, SND 919, SUD 919CL2Y, Sifrol
• Marque: TRC

Description

Applications (S)-Pramipexole enantiomer. A dopamine-D2-receptor agonist. Antiparkinsonian. Pramipexole (Mirapex, Mirapexin, Sifrol) is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease (PD) and restless legs syndrome (RLS).[1] It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants.
References Mierau, J., et al.: J. Med. Chem., 30, 494 (1987), Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992), Kieburtz, K., et al.: J. Am. Med. Assoc., 278, 125 (1997)

Propriétés chimiques

• Masse moléculaire: 211.33
• Formule: C₁₀H₁₇N₃S
• Couleur/Forme: Neat
• InChI: InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1
• Code InChI: InChIKey=FASDKYOPVNHBLU-ZETCQYMHSA-N
• SMILES: CCCN[C@H]1CCc2nc(N)sc2C1