Promethazine Sulfone

CAS : 13754-56-8

Ref. TR-P757015

Informations sur le produit

• Nom: Promethazine Sulfone
• Synonymes: N,N,a-Trimethyl-10H-phenothiazine-10-ethanamine 5,5-Dioxide, Phenothiazine, 10-[2-(dimethylamino)propyl]-, 5,5-dioxide (8CI), 9,9-Dioxopromethazine, 9,9-Dioxypromethazin, Dioxopromethazine, Promethazine 5,5-dioxide, Prothanon, N,N,a-Trimethyl-5,5-dioxide-10H-phenothiazine-10-ethanamine, 10-[2-(dimethylamino)propyl]-5,5-dioxidephenothiazine, 1-(5,5-Dioxido-10H-phenothiazin-10-yl)-N,N-dimethylpropan-2-amine, 1-(5,5-Dioxophenothiazin-10-yl)-N,N-dimethylpropan-2-amine, 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, 5,5-dioxide (9CI), 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, 5,5-dioxide, 10H-phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, 5,5-dioxide, Phenothiazine, 10-[2-(dimethylamino)propyl]-, 5,5-dioxide

Description

Applications Promethazine Sulfone, is a metabolite of Promethazine (P757000), which is a drug from antihistamine family. It has strong sedative effects and in some countries used for the treatment of insomnia. It has also antiemetic and anticholinergic properties.
References Edge, W., et al.: J. Pharm. Pharmacol., 5, 279 (1953), Huang, et al.: J. Pharm. Sci., 59, 772 (1970), Shearer, C.M., et al.: Anal. Profiles Drug Subs., 5, 429 (1976)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 316.42
• Formule: C₁₇H₂₀N₂O₂S
• Couleur/Forme: Neat
• InChI: InChI=1S/C17H20N2O2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)22(20,21)17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3
• Code InChI: InChIKey=FDXKCOBAFGSMDJ-UHFFFAOYSA-N
• SMILES: CC(CN1c2ccccc2S(=O)(=O)c2ccccc21)N(C)C