(Z)-9-(2-Propen-1-ylidene)-2-(trifluoromethyl)-9H-thioxanthene

Ref. TR-P769090

Informations sur le produit

• Nom: (Z)-9-(2-Propen-1-ylidene)-2-(trifluoromethyl)-9H-thioxanthene
• Synonymes: (9Z)-9-prop-2-enylidene-2-(trifluoromethyl)thioxanthene

Description

Applications (Z)-9-(2-Propen-1-ylidene)-2-(trifluoromethyl)-9H-thioxanthene is an intermediate used in the synthesis of (E/Z)-Flupentixol-d4 Dihydrochloride (F597982), which is a neuroleptic agent related structurally to thiothixene. Antipsychotic; neuroleptic agent; dopamine receptor antagonist.
References Nielsen, et al.: Acta Pharmacol. Toxicol., 32, 363 (1973), Post, M.L., et al.: Nature, 256, 342 (1975), Peuch, et al.: Neuropharmacology, 20, 1279 (1981),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 304.329
• Formule: C₁₇H₁₁F₃S
• Couleur/Forme: Neat
• InChI: InChI=1S/C17H11F3S/c1-2-5-12-13-6-3-4-7-15(13)21-16-9-8-11(10-14(12)16)17(18,19)20/h2-10H,1H2/b12-5-
• Code InChI: InChIKey=UIMQNVZBCXVRPK-XGICHPGQSA-N
• SMILES: C=C/C=C1/c2ccccc2Sc2ccc(C(F)(F)F)cc21