Ralfinamide Mesylate

CAS : 202825-45-4

Ref. TR-R075000

Informations sur le produit

• Nom: Ralfinamide Mesylate
• Synonymes: (2S)-2-[[[4-[(2-Fluorophenyl)methoxy]phenyl]methyl]amino]propanamide Methanesulfonate, (S)-Monomethanesulfonate, (S)-2-[[4-[(2-Fluorobenzyl)oxy]benzyl]amino]propanamide Methanesulfonate
• CAS: 202825-45-4

Description

Applications Ralfinamide mesylate is a mixed sodium and N-type calcium channel protein inhibitor. Inhibitory activity of Ralfinamide mesylate is voltage dependent, with higher potency towards inactivated channels. Ralfinamide mesylate is useful in preventing, alleviating and curing a wide range of pathologies, including pain, migraine, peripheral diseases, cardiovascular diseases, inflammatory processes affecting all body systems, disorders affecting skin and related tissues, disorders of the respiratory system, disorders of the immune and endocrinol. systems, gastrointestinal, urogenital, metabolic and seizure disorders.
References Bayes, M., et al.: Methods. Find. Exp. Clin. Pharmacol., 27, 411 (2005); Pevarello, P., et al.: J. Med. Chem., 41, 579 (1998); Bauer, M., et al.: Pharmacol., 85, 297 (2010);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 398.449
• Formule: C₁₈H₂₃FN₂O₅S
• Couleur/Forme: White Solid
• InChI: InChI=1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-6-8-15(9-7-13)22-11-14-4-2-3-5-16(14)18;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1
• Code InChI: InChIKey=CHQVNINIGBRKGZ-YDALLXLXSA-N
• SMILES: CS(=O)(=O)O.C[C@H](NCc1ccc(OCc2ccccc2F)cc1)C(N)=O