Retrorsine-D4

CAS : 480-54-6

Ref. TR-R279002

Informations sur le produit

• Nom: Retrorsine-D4
• Synonymes: (3Z,5R,6S,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione-D4, 12,18-Dihydroxy-senecionan-11,16-dione-D4, NSC 107659-D4, Retrorsin-D4, [5R-(3Z,5R*,6S*,14aR*,14bR*)]-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione-D4, β-Longilobine-D4, (1,6)Dioxacyclododecino(2,3,4-gh)pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-, (3Z,5R,6S,14aR,14bR)-, (15Z)-12,18-dihydroxysenecionan-11,16-dione, (3Z,5R,6S,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 12,18-Dihydroxy-senecionan-11,16-dione, 3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-hydroxymethyl-5-methyl(1,6)dioxacyclododeca(2,3,4-gh)pyrrolizidine-2,7-dione, Ccris 4338, Hsdb 3530, Nsc 107659, Retrorsin, Senecionan-11,16-dione, 12,18-dihydroxy-, Senecionan-11,16-dione, 12,18-dihydroxy- (9CI), [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-, [5R-(3Z,5R*,6S*,14aR*,14bR*)]-, beta-Longilobine, cis-Retronecic acid ester of retronecine, trans-15-Ethylidene-12beta-hydroxy-12alpha-hydroxymethyl-13beta-methylsenec-1-enine, β-Longilobine, Retrorsine

Description

Applications Retrorsine-D4 is a labelled analogue of Retrorsine (R279000). Retrorsine is a pyrrolizidine alkaloid that blocks the hepatocyte cell cycle, ultimately affecting hepatocyte proliferative capacity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gordon, G., et al.: Hepatology, 32, 312 (2000); Laconi, E., et al.: Am. J. Path., 153, 319 (1998)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 355.419
• Formule: C₁₈H₂₁D₄NO₆
• InChI: InChI=1S/C18H25NO6/c1-3-12-8-11(2)18(23,10-20)17(22)24-9-13-4-6-19-7-5-14(15(13)19)25-16(12)21/h3-4,11,14-15,20,23H,5-10H2,1-2H3/b12-3-/t11-,14-,15-,18-/m1/s1/i6D2,9D2
• Code InChI: InChIKey=BCJMNZRQJAVDLD-HNOQTVLNSA-N
• SMILES: [2H]C1([2H])OC(=O)[C@@](O)(CO)[C@H](C)C/C(=C/C)C(=O)O[C@@H]2CCN3[C@@H]2C1=CC3([2H])[2H]