Rifabutin N-Oxide

CAS : 645406-37-7

Ref. TR-R505020

Informations sur le produit

• Nom: Rifabutin N-Oxide
• Synonymes: Rifabutin N-oxide,Spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2',3':7,8]naphth[1,2-d]imidazole-2,4'-piperidine]-5,10,26(3H,9H)-trione, 16-(acetyloxy)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-, 1'-oxide, (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-

Description

Stability Hygroscopic, Light Sensitive
Applications Rifabutin N-Oxide is a metabolite of Rifabutin (R505000) and like its parent compound it exhibits antibacterial activity.
References Medeiros, M., et al.: PCT Int. Appl., 44, (2004); Anand, R., et al.: Antimicrob. AG. Chemother., 32 (684 (1988), Skinner, M.H., et al.: Antimicrob. Agent Chemother., 33, 1237 (1989),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 863.00
• Formule: C₄₆H₆₂N₄O₁₂
• Couleur/Forme: Dark Red
• InChI: InChI=1S/C46H62N4O12/c1-22(2)21-50(58)18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,62-42)60-20-15-30(59-11)25(5)41(61-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/b13-12+,20-15+,24-14-/t23-,25+,26+,27+,30-,37-,38+,41+,45-,46?,50?/m0/s1
• Code InChI: InChIKey=HVQQNDMUDPTBRO-ZZKRMFRKSA-N
• SMILES: CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C)c(O)c4c(c3C2=O)C2=NC3(CC[N+]([O-])(CC(C)C)CC3)NC2=C(NC(=O)/C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)C4=O