Rucaparib

CAS : 283173-50-2

Ref. TR-R701580

Informations sur le produit

• Nom: Rucaparib
• Synonymes: 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one, 8-Fluoro-2-[4-[(methylamino)methyl]phenyl]-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, Rubraca, 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-azepino[5,4,3-cd]indol-6-one, 6H-Azepino[5,4,3-cd]indol-6-one,8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-
• CAS: 283173-50-2

Description

Applications Rucaparib is PARP1 inhibitor. It can be used in biological study of chemical screening to identify drugs that enhance or mitigate cellular responses to antibody-toxin fusion proteins using human B cell precursor leukemia cells and cervical adenocarcinoma cells.
References Antignani, A., et al.: PLoS One, 11, e0161415/1-e0161415/17 (2016)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 323.36
• Formule: C₁₉H₁₈FN₃O
• Couleur/Forme: Neat
• InChI: InChI=1S/C19H18FN3O/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24)
• Code InChI: InChIKey=HMABYWSNWIZPAG-UHFFFAOYSA-N
• SMILES: CNCc1ccc(-c2[nH]c3cc(F)cc4c3c2CCNC4=O)cc1