Scopolamine N-Oxide

CAS : 97-75-6

Ref. TR-S200020

Informations sur le produit

• Nom: Scopolamine N-Oxide
• Synonymes: (aS)-a-(Hydroxymethyl)benzeneacetic Acid (1a,2ß,4ß,5a,7ß)-9-Methyl-9-oxido-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl Ester, 6ß,7ß-Epoxy-1aH,5aH-tropan-3a-ol (-)-Tropate 8-Oxide, [7(S)-(1a,2ß,4ß,5a,7ß)]-a-(Hydroxymethyl)benzeneacetic Acid 9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl Ester N-Oxide, Scopolamine, N-Oxide, 3-Oxa-9-azatricyclo[3.3.1.02,4]nonane Benzeneacetic Acid Deriv., Genoscopolamine, Hyoscinamine Oxide, Hyoscine N-Oxide, Hyoscineamine Oxide, Oxicopolamina, Scolamine, Scolen, Scopodex, Scopolamine aminoxide, Seamalin, Seronex, (1S,2R,4S,5S)-9-methyl-9-oxido-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl 3-hydroxy-2-phenylpropanoate, 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-ol, 6β,7β-epoxy-, (-)-tropate (ester), 8-oxide, 3-Oxa-9-azatricyclo[3.3.1.0^2,4]nonane, benzeneacetic acid deriv., Benzeneacetic acid, alpha-(hydroxymethyl)-, (1alpha,2beta,4beta,5alpha,7beta)-9-methyl-9-oxido-3-oxa-9-azatricyclo(3.3.1)non-7-yl ester, (alphaS)-, Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-9-oxido-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, (αS)-, Benzeneacetic acid, α-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, N-oxide, [7(S)-(1α,2β,4β,5α,7β)]-, Hyoscinamide oxide, Hyoscinamine oxide, Hyoscineamine oxide, Oxicopolamine, Scopolamine N-oxide
• CAS: 97-75-6

Description

Stability Hygroscopic
Applications Scopolamine N-Oxide is an impurity of Scopolamine (S200000), an acetylcholine antagonist used in the treatment of motion sickness and also used as antiemetic, antispasmodic, mydriatic, preanesthetic agents.
References Shahwar, D., et al.: Turk. J. Chem., 36, 257 (2012); Paula, S., et al.: J. Med. Chem., 47, 133 (2004); Wu, H.L., et al.: J. Chromatograph. A., 802, 107 (1998); Phillipson, J.D., et al.: J. Pharma. Pharmcol., 25, 116 (1973);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 319.35
• Formule: C₁₇H₂₁NO₅
• Couleur/Forme: Neat
• InChI: InChI=1S/C17H21NO5/c1-18(21)13-7-11(8-14(18)16-15(13)23-16)22-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11-,12-,13-,14+,15-,16+,18?/m1/s1
• Code InChI: InChIKey=GSYQNAMOFFWAPF-PPOBMCMBSA-N
• SMILES: C[N+]1([O-])[C@H]2C[C@H](OC(=O)[C@H](CO)c3ccccc3)C[C@@H]1[C@H]1O[C@@H]21