Simvastatin-d6 Hydroxy Acid Ammonium Salt

CAS : 139893-43-9

Ref. TR-S485022

Informations sur le produit

• Nom: Simvastatin-d6 Hydroxy Acid Ammonium Salt
• Synonymes: (ßR,dR,1S,2S,6R,8S,8aR)-8-[2,2-(Dimethyl-d6)-1-oxobutoxy]-1,2,6,7,8,8a-hexahydro-ß,d-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Ammonium Salt, Simvastatin-d6 Acid Ammonium Salt, Simvastatin-d6 Ammonium Salt, Simvastatin-d6 Carboxylic Acid Ammonium Salt, (3R,5R)-7-((1S,2S,6R,8S,8aR)-8-(2,2-dimethylbutanoyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)-3,5-dihydroxyheptanoate ammonium salt, 1-Naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a, 1-Naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-,d-dihydroxy-2,6-dimethyl-, monoammonium salt, (R,dR,1S,2S,6R,8S,8aR)-, 1-Naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-, ammonium salt (1:1), (βR,δR,1S,2S,6R,8S,8aR)-, 1-Naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-, monoammonium salt, (βR,δR,1S,2S,6R,8S,8aR)-, 1-Naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-, monoammonium salt, [1S-[1α(βS*,δS*),2α,6β,8β,8aα]]-, Ammonium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-(2,2-dimethylbutyryloxy)-1,2,6,7,8,8a-hexahydro-2,6-dimethyl-1-naphthyl]-3,5-dihydroxyheptanoate, Ammonium simvastatin, Simvastatin Ammouium Salt, Simvastatin Hydroxy Acid, Ammonium Salt, Simvastatin acid ammonium salt, Simvastatin carboxylic acid ammonium salt, Simvastatin hydroxyl acid ammonium salt, Simvastatin impurity A, Simvastatin ammonium salt

Description

Applications A deuterated metabolite of Simvastin (S485000). A competitive inhibitor of HMG-CoA reductase.
References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 459.65
• Formule: C₂₅H₃₇D₆NO₆
• Couleur/Forme: White To Light Orange Colour
• SMILES: [2H]C([2H])([2H])C(CC)(C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@H](O)C[C@H](O)CC(=O)[O-])[C@H]21)C([2H])([2H])[2H].[NH4+]