Sivelestat Sodium

CAS : 150374-95-1

Ref. TR-S497060

Informations sur le produit

• Nom: Sivelestat Sodium
• Synonymes: N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-glycine Monosodium Salt, ONO 5046-Na, Sodium Sivelestat, Glycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, Propanoic acid, 2,2-dimethyl-, 4-[[[2-[[(carboxymethyl)amino]carbonyl]phenyl]amino]sulfonyl]phenyl ester, sodium salt (1:1), Sodium ({2-[({4-[(2,2-dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}amino)acetate, Sodium sivelestat

Description

Applications Sivelestat Sodium is an inhibitor of neutrophil elastase. Also, it is a promising therapeutic agent for severe acute pneumonitis caused by gefitinib.
References Sercundes, M. K., et al.: Plos Pathog., 12, 1006054/1-1006054/24 (2016); Mikumo, H., et al.: Biochem. Biophys. Res. Commun., 486, 205-209 (2017)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 456.44
• Formule: C₂₀H₂₁N₂NaO₇S
• Couleur/Forme: Neat
• InChI: InChI=1S/C20H22N2O7S.Na/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24;/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24);/q;+1/p-1
• Code InChI: InChIKey=ZAIFANJZUGNYCK-UHFFFAOYSA-M
• SMILES: CC(C)(C)C(=O)Oc1ccc(S(=O)(=O)Nc2ccccc2C(=O)NCC(=O)O[Na])cc1