SN-38 Carboxylate Disodium Salt

CAS : 142677-15-4

Ref. TR-S589960

Informations sur le produit

• Nom: SN-38 Carboxylate Disodium Salt
• Synonymes: (αS)-α,12-Diethyl-9,11-dihydro-α,2-dihydroxy-8-(hydroxymethyl)-9-oxo-9-indolizino[1,2-b]quinoline-7-acetic Acid Disodium Salt, SN 38 Acid Sodium Salt
• CAS: 142677-15-4

Description

Applications The active metabolite of Irinotecan (carboxylate form). SN-38 lactone and carboxylate may be considered pharmacokinetically distinct agents.
References Billecke, S., et al.: Drug Metab. Dispos., 28, 1335 (2000), Teiber, J., et al.: Biochem. Pharmacol., 66, 887 (2003), Ashley, G., et al.: J. Antibiot., 57, 224 (2004),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 454.39
• Formule: C₂₂H₂₀N₂Na₂O₆
• Couleur/Forme: Neat
• InChI: InChI=1S/C22H22N2O6.2Na/c1-3-12-13-7-11(26)5-6-17(13)23-19-14(12)9-24-18(19)8-16(15(10-25)20(24)27)22(30,4-2)21(28)29;;/h5-8,25-26,30H,3-4,9-10H2,1-2H3,(H,28,29);;/q;2*+1/p-2/t22-;;/m0../s1
• Code InChI: InChIKey=OPIACBXCNWXXGI-IKXQUJFKSA-L
• SMILES: CCc1c2c(nc3ccc(O[Na])cc13)-c1cc([C@@](O)(CC)C(=O)O[Na])c(CO)c(=O)n1C2