Spironolactone

CAS : 52-01-7

Ref. TR-S683000

Informations sur le produit

• Nom: Spironolactone
• Synonymes: Abbolactone, Aldace, Aldactone, Aldactone A, Aldopur, Almatol, Altex, Aquareduct, Berlactone, Deverol, Diatensec, Dira, Duraspiron, Euteberol, Lacalmin, Lacdene, Laractone, NSC 150399, Nefurofan, Novo-Spiroton, Osiren, Osyrol, Quimolactona, SC 9420, Sagisal, Sincomen, Spiresis, Spiretic, Spiridon, Spiro-Tablinen, Spiroctan, Spiroderm, Spirolactone, Spirolang, Spirolone, Spirone, Spironol, Spironolactone A, Supra-Puren, Suracton, Uractone, Urusonin, Verospiron, Verospirone, Xenalon,Spironolactone, (2'R)-7α-(Acetylsulfanyl)-3',4'-dihydro-5'H-spiro[androst-4-ene-17,2'-furan]-3,5'-dione, Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, γ-lactone, (7α,17α)-, 17α-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7α-mercapto-3-oxo-, γ-lactone, acetate (6CI,8CI), Spiro[17H-cyclopenta[a]phenanthrene-17,2'(5'H)-furan], pregn-4-ene-21-carboxylic acid deriv., 17-Hydroxy-7α-mercapto-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone 7-acetate, 3-(3-Oxo-7α-acetylthio-17β-hydroxy-4-androsten-17α-yl)propionic acid-γ-lactone, 3-(3-keto-7α-Acetylthio-17β-hydroxy-4-androsten-17α-yl)propionic acid lactone, 3'-(3-Oxo-7α-acetylthio-17β-hydroxyandrost-4-en-17α-yl)-propionic acid lactone, 7α-(Acetylthio)-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone
• Marque: TRC
• Description: Applications It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.References Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975),

Propriétés chimiques

• Masse moléculaire: 416.57
• Formule: C₂₄H₃₂O₄S
• Couleur/Forme: Off-White
• InChI: InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1
• Code InChI: InChIKey=LXMSZDCAJNLERA-ZHYRCANASA-N
• SMILES: CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@]34CCC(=O)O4)[C@@H]21