Succinylacetone

CAS : 51568-18-4

Ref. TR-S692060

Informations sur le produit

• Nom: Succinylacetone
• Synonymes: 4,6-dioxoheptanoic acid, Ccris 1387, Heptanoic acid, 4,6-dioxo-, Nsc 174804, Succinyl acetone

Description

Applications Succinylacetone (SA) is a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. It was developed a stable-isotope for the determination of SA in dried blood spots (DBS) and liquid urine using a 13C4-SA as internal standard. The method was applied retrospectively and prospectively for the diagnosis of hepatorenal tyrosinemia and for follow-up of patients under treatment.
References Kvittingen, E., et al.: Inher. Metab. Dis., 14, 554 (1991), Lindstedt, S., et al.: Lancet, 340, 813 (1992), Schulze, A., et al.: Clin. Chem., 47, 1424 (2001), Allard, P., et al.: Clin. Biochem., 37, 1010 (2004),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 158.15
• Formule: C₇H₁₀O₄
• Couleur/Forme: White To Off-White
• InChI: InChI=1S/C7H10O4/c1-5(8)4-6(9)2-3-7(10)11/h2-4H2,1H3,(H,10,11)
• Code InChI: InChIKey=WYEPBHZLDUPIOD-UHFFFAOYSA-N
• SMILES: CC(=O)CC(=O)CCC(=O)O