(Z)-Sulindac Sulfone

CAS : 59973-80-7

Ref. TR-S699225

Informations sur le produit

• Nom: (Z)-Sulindac Sulfone
• Synonymes: 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-, (Z)-, (1Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic acid, Aptosyn, Exisulind, FGN 1, Prevatec, Sulindac sulfone, cis-5-Fluoro-2-methyl-1-[p-methylsulfonylbenzylidenyl]indene-3-acetic acid, Sulindac Related Compound B, Sulindac Impurity B,(Z)-[5-Fluoro-2-methyl-1-[4-(methylsulfonyl)benzylidene]-1H-inden-3-yl]acetic Acid (Sulindac Sulfone), (1Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic Acid, 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-, (1Z)-, 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-, (Z)-, Aposulind, Fgn-1, Prevatac(former Brand Name)

Description

Stability Hygroscopic
Applications An active metabolite of Sulindac. Inducer of apoptosis independent of cyclooxygenase inhibition. Inhibits cell growth by inducing apoptosis.
References Piazza, G.A., et al.: Cancer Res., 55, 3310 (1995)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 372.41
• Formule: C₂₀H₁₇FO₄S
• Couleur/Forme: Neat
• InChI: InChI=1S/C20H17FO4S/c1-12-17(9-13-3-6-15(7-4-13)26(2,24)25)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-
• Code InChI: InChIKey=MVGSNCBCUWPVDA-MFOYZWKCSA-N
• SMILES: CC1=C(CC(=O)O)c2cc(F)ccc2/C1=C\c1ccc(S(C)(=O)=O)cc1