4'-Sulphated Lewis X, Methyl Glycoside Sodium Salt

CAS : 386229-72-7

Ref. TR-S699300

Informations sur le produit

• Nom: 4'-Sulphated Lewis X, Methyl Glycoside Sodium Salt
• Synonymes: 4'-SO4-Gal1-b-4[Fuc1-alpha-3]GlcNAc-b-O-Me, Methyl O-2-alpha-3-O-(4-sulfo-b-D-galactopyranosyl)-1-b-4-O-[(alpha-L-fucopyranosyl)-1-alpha-3]-2-alphacetamido-2-deoxy-b-D-glucopyranoside Sodium Salt

Description

Applications Recently shown to be a good ligand for E- and L-selectins, two calcium-dependent mammalian lectins associated with early steps in the inflammatory response and lymphocyte extravasation into peripheral lymph nodes which makes them good candidates for anti-inflammatory drugs.
References Yuen, C.T., et al.: J. Biol. Chem., 269, 1595 (1994), Lubineau, A., et al.: Tetrahedron Letters, 35, 47, 8795 (1994)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 645.561
• Formule: C₂₁H₃₆NNaO₁₈S
• Couleur/Forme: Off-White
• InChI: InChI=1S/C21H37NO18S.Na/c1-6-11(26)12(27)14(29)20(35-6)39-17-10(22-7(2)25)19(34-3)36-8(4-23)16(17)38-21-15(30)13(28)18(9(5-24)37-21)41(32,33)40-31;/h6,8-21,23-24,26-31H,4-5H2,1-3H3,(H,22,25);/q;+1/p-1/t6-,8+,9+,10+,11+,12+,13?,14?,15+,16+,17+,18-,19+,20-,21-;/m0./s1
• Code InChI: InChIKey=DRCMLSXBDUEPFY-VYZRZESDSA-M
• SMILES: CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](S(=O)(=O)OO[Na])C(O)[C@H]2O)[C@H](O[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)C2O)[C@H]1NC(C)=O