Tamibarotene

CAS : 94497-51-5

Ref. TR-T005800

Informations sur le produit

• Nom: Tamibarotene
• Synonymes: 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid, 4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]benzoic acid, AM80, Retinoid AM 80, 4-[(5,5,8,8-Tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid, 4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]benzoic Acid, Amnolake, 4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid, Am 80 (pharmaceutical), NSC 608000, Am 80, Am 80 (pharmaceutical), Benzoic acid, 4-[[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]-

Description

Applications Synthetic retinoic acid receptor-α/β-selective retinoid. Antineoplastic.
References Hashimoto, Y., et al.: Jpn. J. Cancer Res., 79, 473 (1988), Mizojiri, K., et al.: Arzneim.-Forsch., 47, 59 (1997), Shinjo, K., et al.: Int. J. Hematol., 72, 470 (2000), Sanda, T., et al.: Leukemia, 19, 901 (2005),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 351.44
• Formule: C₂₂H₂₅NO₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-16(9-10-17(18)21)23-19(24)14-5-7-15(8-6-14)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26)
• Code InChI: InChIKey=MUTNCGKQJGXKEM-UHFFFAOYSA-N
• SMILES: CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(C(=O)O)cc3)ccc21