Tamoxifen-d5

CAS : 157698-32-3

Ref. TR-T006077

Informations sur le produit

• Nom: Tamoxifen-d5
• Synonymes: Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl-3,3,4,4,4-d5]phenoxy]-N,N-dimethyl-, Ethanamine, 2-[4-(1,2-diphenyl-1-butenyl-3,3,4,4,4-d5)phenoxy]-N,N-dimethyl-, (Z)-, Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-butenyl-3,3,4,4,4-d5]phenoxy]-N,N-dimethyl- (9CI), 2-[4-[(1Z)-1,2-Diphenyl-1-buten-1-yl-3,3,4,4,4-d5]phenoxy]-N,N-dimethylethanamine, Z-Tamoxifen-d5, trans-Tamoxifen-d5, Tamoxifen-D5 (ethyl-D5), ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl-3,3,4,4,4-d_5_]phenoxy]-N,N-dimethyl-

Description

Applications Labelled Tamoxifen (T006000). A nonsteroidal estrogen antagonist of interest in the treatment of some forms of breast cancer. Tamoxifen is a protein kinase C inhibitor, and induces apoptosis in human malignant glioma cell lines.
References Sutherland, R., et al.: Nature, 267, 434 (1977), Lerner, L., et al.: Cancer Res., 50, 4177 (1990), Love, R., et al.: J. Clin. Oncol., 20 2559 (2002),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 376.55
• Formule: C₂₆H₂₄D₅NO
• Couleur/Forme: Neat
• InChI: InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-/i1D3,4D2
• Code InChI: InChIKey=NKANXQFJJICGDU-FUYVPVGLSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])/C(=C(\c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1