Taurodeoxycholic Acid Sodium Salt

CAS : 1180-95-6

Ref. TR-T009005

Informations sur le produit

• Nom: Taurodeoxycholic Acid Sodium Salt
• Synonymes: Ethanesulfonic acid, 2-[[(3a,5ß,12a)-3,12-dihydroxy-24-oxocholan-24-yl]amino]-, monosodium salt, Taurine, N-(3a,12a-dihydroxy-5ß-cholan-24-oyl)-, monosodium salt (8CI), Taurodeoxycholic acid sodium salt (6CI), Cholane, ethanesulfonic acid deriv., STDC, Sodium 3a,12a-dihydroxy-5ß-cholanoyltaurate, Sodium deoxytaurocholate, Sodium taurodeoxycholate, Sodium taurodesoxycholate, Taurodeoxycholate sodium, Cholane, ethanesulfonic acid deriv., Ethanesulfonic acid, 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]-, monosodium salt, Sodium 2-(((3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl)amino)ethane-1-sulphonate, Sodium 2-[(3,7-Dihydroxy-24-Oxocholan-24-Yl)Amino]Ethyl Sulfate, Sodium 2-{[(3Alpha,5Beta,12Alpha)-3,12-Dihydroxy-24-Oxocholan-24-Yl]Amino}Ethanesulfonate, Sodium 3α,12α-dihydroxy-5β-cholanoyltaurate, Taurine, N-(3α,12α-dihydroxy-5β-cholan-24-oyl)-, monosodium salt, Taurodeoxycholic acid sodium salt, Unii-5Pe424S83L

Description

Applications Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.
References Cheng, K., et al.: Biochem. J., 330, 353 (1998), Cheng, K., et al.: Cancer Res., 63, 6744 (2003), Bellacosa, A., et al.: Adv. Cancer Res., 94, 29 (2005), Cheng, K., et al.: Biochem. Pharmacol., 70, 1035 (2005), Fang, D., et al.: J. Biol. Chem., 282, 11221 (2007),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 521.69
• Formule: C₂₆H₄₄NO₆S·Na
• Couleur/Forme: Off-White
• InChI: InChI=1S/C26H45NO6S.Na/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/q;+1/p-1/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;/m1./s1
• SMILES: C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@@]21C.[Na+]