Tenofovir

CAS : 147127-20-6

Ref. TR-T018500

Informations sur le produit

• Nom: Tenofovir
• Synonymes: Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- (9CI), Phosphonic acid, [[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, (R)-, P-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid, (R)-9-(2-Phosphonomethoxypropyl)adenine, ([[(2R)-1-(6-Amino-9H-purin-9-yl)propan-2-yl]oxy]methyl)phosphonic acid, GS 1275, GS 1278, PMPA, TDF, Tenefovir
• Marque: TRC

Description

Applications Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral.
References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);

Propriétés chimiques

• Masse moléculaire: 287.21
• Formule: C₉H₁₄N₅O₄P
• Couleur/Forme: Neat
• InChI: InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1
• Code InChI: InChIKey=SGOIRFVFHAKUTI-ZCFIWIBFSA-N
• SMILES: C[C@H](Cn1cnc2c(N)ncnc21)OCP(=O)(O)O