Tenofovir Monoisoproxil Dimer Ammonium Sodium Salt (>85%)

Ref. TR-T018550

Informations sur le produit

• Nom: Tenofovir Monoisoproxil Dimer Ammonium Sodium Salt (>85%)
• Synonymes: ((Hydroxy((((2R)-1-(4-((((1-((2R)-2-((hydroxyhydrophosphoryl)methoxy)propyl)-1H-benzo[d]imidazol-4-yl)amino)methyl)amino)-1H-benzo[d]imidazol-1-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(oxy))bis(methylene) Diisopropyl Dicarbonate Ammonium Sodium Salt

Description

Stability Light Sensitive, Temperature Sensitive, Very Hygroscopic
Applications Tenofovir Monoisoproxil Dimer Ammonium Sodium Salt is an impurity in the synthesis of Tenofovir disoproxil (T018505),an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor.
References Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 816.65 + x(22.99) + x(17.03)
• Formule: C₂₉H₄₂N₁₀O₁₄P₂•x(Na)•x(NH₃)
• Degré de pureté: >85%
• Couleur/Forme: Neat
• InChI: InChI=1S/C29H44N10O14P2.H3N.Na/c1-18(2)52-28(40)46-14-50-54(42,43)16-48-20(5)7-38-12-36-22-24(32-10-34-26(22)38)30-9-31-25-23-27(35-11-33-25)39(13-37-23)8-21(6)49-17-55(44,45)51-15-47-29(41)53-19(3)4;;/h10-13,18-21H,7-9,14-17H2,1-6H3,(H,42,43)(H,44,45)(H,30,32,34)(H,31,33,35);1H3;/q;;+1/p-1
• Code InChI: InChIKey=HONHJROATOKUHX-NHCUHLMSSA-L
• SMILES: CC(C)OC(=O)OCOP(=O)([O-])CO[C@H](C)Cn1cnc2c(NCNc3ncnc4c3ncn4C[C@@H](C)OCP(=O)([O-])OCOC(=O)OC(C)C)ncnc21