Tepoxalin

CAS : 103475-41-8

Ref. TR-T103250

Informations sur le produit

• Nom: Tepoxalin
• Synonymes: 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]-N-hydroxy-N-methylpropanamide, 1H-Pyrazole-3-propanamide, 5-(4-chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-, 3-(5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-pyrazolyl)-N-hydroxy-N-methylpropanamide, 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl]-N-hydroxy-N-methylpropanamide, 5-(4-Chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-1H-pyrazole-3-propanamide, 5-(p-Chlorophenyl)-1-(p-methoxyphenyl)-N-methylpyrazole-3-propionohydroxamic acid, Orf 20485, Rwj 20485, Tepoxalin [USAN:INN], Tepoxalina, Tepoxalina [Spanish], Tepoxaline, Tepoxaline [French], Tepoxalinum, Tepoxalinum [Latin], Unii-Tz4Ox61974, Zubrin

Description

Applications Non-steroidal anti-inflammatory drug (NSAID) with potent anti-inflammatory and analgesic properties approved for veterinary use. It has inhibitory effect on cyclooxygenase and 5-lipxygenase activity as well as inhibiting the production of cytokines in peripheral cells outside the CNS.
References Argentieri, D.C. et al.: J. Pharmacol. Exp. Therap., 271, 1399 (1994); Agnello, K.A. et al.: Am. J. Vet. Res., 66, 966 (2005); Fiebich, B.L. et al.: Neuropharmacol., 38, 1325 (1999);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 385.84
• Formule: C₂₀H₂₀ClN₃O₃
• Couleur/Forme: White Crystalline
• InChI: InChI=1S/C20H20ClN3O3/c1-23(26)20(25)12-7-16-13-19(14-3-5-15(21)6-4-14)24(22-16)17-8-10-18(27-2)11-9-17/h3-6,8-11,13,26H,7,12H2,1-2H3
• Code InChI: InChIKey=XYKWNRUXCOIMFZ-UHFFFAOYSA-N
• SMILES: COc1ccc(-n2nc(CCC(=O)N(C)O)cc2-c2ccc(Cl)cc2)cc1