7,8,9,10-Tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine 1,4-Dioxide

CAS : 1337563-47-9

Ref. TR-T293955

Informations sur le produit

• Nom: 7,8,9,10-Tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine 1,4-Dioxide

Description

Applications 7,8,9,10-Tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine 1,4-Dioxide, is an impurity of Varenicline (V098490), a nicotinic α4β2 acetylcholine receptor partial agonist. Aid in smoking cessation.
References Benowitz, N., et al.: Clin. Pharmacol. Ther., 44, 23 (1988), Cohen, C., et al.: J. Pharmacol. Exp. Ther., 306, 407 (2003), Tapper, A., et al.: Science, 306, 1029 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Obach, R., et al.: Drug Metab. Disp., 34, 121 (2006),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 243.26
• Formule: C₁₃H₁₃N₃O₂
• Couleur/Forme: Neat
• SMILES: [O-][n+]1cc[n+]([O-])c2cc3c(cc21)C1CNCC3C1