5,6,7,8-Tetrahydro-1-naphthalenol

CAS : 529-35-1

Ref. TR-T294265

Informations sur le produit

• Nom: 5,6,7,8-Tetrahydro-1-naphthalenol
• Synonymes: 1,2,3,4-Tetrahydro-5-hydroxynaphthalene, 1,2,3,4-Tetrahydro-5-naphthol, 1,2,3,4-Tetrahydronaphthalen-5-ol, 1-Hydroxy-5,6,7,8-tetrahydronaphthalene, 1-Naphthalenol, 5,6,7,8-tetrahydro-, 1-Naphthol, 5,6,7,8-tetrahydro-, 5,6,7,8-Tetrahydro-1-hydroxynaphthalene, 5,6,7,8-Tetrahydro-alpha-naphthol, 5,6,7,8-Tetrahydro-α-naphthol, 5,6,7,8-Tetrahydronaphthalen-1-Ol, 5,6,7,8-Tetrahydronaphthol, 5-Hydroxytetralin, Nsc 28822, Tetrahydro-alpha-naphthol, Tetrahydro-α-naphthol, Tetralin-5-ol, 5,6,7,8-Tetrahydro-1-naphthol

Description

Applications 5,6,7,8-Tetrahydro-1-naphthalenol was used as a reagent in the synthesis of phosphonamidate and phosphonodiamidate prodrugs of adefovir and tenofovir which are used in the treatment of HIV infections. Also used in the synthesis of tetrahydronaphthalene-1-ol derivatives which were found to be promising potent antitumor agents.
References Pertusati, F., et al.: Eur. J. Med. Chem., 78, 259 (2014); Dong, Y., et al.: Bioorg. Med. Chem. Lett., 19, 6289 (2009);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 148.2
• Formule: C₁₀H₁₂O
• Couleur/Forme: Neat
• InChI: InChI=1S/C10H12O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h3,5,7,11H,1-2,4,6H2
• Code InChI: InChIKey=SCWNNOCLLOHZIG-UHFFFAOYSA-N
• SMILES: Oc1cccc2c1CCCC2