(R)-(+)-Thalidomide

CAS : 2614-06-4

Ref. TR-T338855

Informations sur le produit

• Nom: (R)-(+)-Thalidomide
• Synonymes: (R)-(+)-2-(2,6-Dioxo-3-piperidinyl)-1H-iso-indole-1,3(2H)-dione, NSC 91729, (+)-Thalidomide, 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (R)-, 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (R)- (9CI), 1H-Isoindole-1,3(2H)-dione, 2-[(3R)-2,6-dioxo-3-piperidinyl]-, 2-[(3R)-2,6-Dioxo-3-piperidinyl]-1H-isoindole-1,3(2H)-dione, 2-[(3R)-2,6-Dioxopiperidin-3-yl]-2,3-dihydro-1H-isoindole-1,3-dione, D-Thalidomide, Phthalimide, N-(2,6-dioxo-3-piperidyl)-, (+)-, Phthalimide, N-(2,6-dioxo-3-piperidyl)-, <span class="text-smallcaps">D</span>-(+)-, Phthalimide, N-(2,6-dioxo-3-piperidyl)-, D-(+)-, R-(+)-Thalidomide, R-(<span class="text-smallcaps">D</span>)-Thalidomide, R-Lenalidomide

Description

Applications Optically active isomer of Thalidomide, which inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative.
References D’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994), Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993), Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 258.23
• Formule: C₁₃H₁₀N₂O₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)/t9-/m1/s1
• Code InChI: InChIKey=UEJJHQNACJXSKW-SECBINFHSA-N
• SMILES: O=C1CC[C@@H](N2C(=O)c3ccccc3C2=O)C(=O)N1