Tiplaxtinin

CAS : 393105-53-8

Ref. TR-T444895

Informations sur le produit

• Nom: Tiplaxtinin
• Synonymes: Tiplasinin, PAI 039, a-Oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-acetic Acid, 1H-Indole-3-acetic acid, α-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-, 1H-indole-3-acetic acid, alpha-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-, Pai 039, α-Oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-acetic acid
• CAS: 393105-53-8

Description

Applications Tiplaxtinin inhibits smooth muscle cells (SMC) migration and intimal hyperplasia. A novel therapeutic agent to improve diabetic wound.
References Ji, Y., et al.: Arterioscler. Thromb. Vasc. Biol., 36, 2167-2175 (2016); Rebalka, I. A., et al.: Diabetes, 64, 2593-2602 (2015)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 439.38
• Formule: C₂₄H₁₆F₃NO₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C24H16F3NO4/c25-24(26,27)32-18-9-6-16(7-10-18)17-8-11-21-19(12-17)20(22(29)23(30)31)14-28(21)13-15-4-2-1-3-5-15/h1-12,14H,13H2,(H,30,31)
• Code InChI: InChIKey=ODXQFEWQSHNQNI-UHFFFAOYSA-N
• SMILES: O=C(O)C(=O)c1cn(Cc2ccccc2)c2ccc(-c3ccc(OC(F)(F)F)cc3)cc12