4-(4-(4-(4H-1,2,4-Triazol-4-yl)phenyl)piperazin-1-yl)phenyl Acetate

Ref. TR-T767468

Informations sur le produit

• Nom: 4-(4-(4-(4H-1,2,4-Triazol-4-yl)phenyl)piperazin-1-yl)phenyl Acetate
• Synonymes: [4-[4-[4-(1,2,4-triazol-4-yl)phenyl]piperazin-1-yl]phenyl] acetate
• Marque: TRC
• Description: Applications 4-(4-(4-(4H-1,2,4-Triazol-4-yl)phenyl)piperazin-1-yl)phenyl Acetate is an intermediate in the synthesis of Deoxo Anhydro Itraconazole Bromide (D231675). Deoxo Anhydro Itraconazole Bromide is an impurity of Itraconazole (I937500), which is orally active antimycotic drug structurally related to Ketoconazole (K186000). Antifungal.References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984); Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989); Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993)

Propriétés chimiques

• Masse moléculaire: 363.413
• Formule: C₂₀H₂₁N₅O₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C20H21N5O2/c1-16(26)27-20-8-6-18(7-9-20)24-12-10-23(11-13-24)17-2-4-19(5-3-17)25-14-21-22-15-25/h2-9,14-15H,10-13H2,1H3
• Code InChI: InChIKey=LILUVKXYXBODFN-UHFFFAOYSA-N
• SMILES: CC(=O)Oc1ccc(N2CCN(c3ccc(-n4cnnc4)cc3)CC2)cc1