N-(4-(4-(4-(((2R,4S)-2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)hydrazinecarboxamide

CAS : 89848-13-5

Ref. TR-T767480

Informations sur le produit

• Nom: N-(4-(4-(4-(((2R,4S)-2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)hydrazinecarboxamide
• Marque: TRC
• Description: Applications N-(4-(4-(4-(((2R,4S)-2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)hydrazinecarboxamide is an intermediate in the synthesis of derivatives of Itraconazole (I937500), an orally active antimycotic and antifungal compound.References Heeres, J., et al.: J. Med. Chem., 27. 894 (1984)

Propriétés chimiques

• Masse moléculaire: 639.53
• Formule: C₃₀H₃₂Cl₂N₈O₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C30H32Cl2N8O4/c31-21-1-10-27(28(32)15-21)30(18-40-20-34-19-35-40)43-17-26(44-30)16-42-25-8-6-24(7-9-25)39-13-11-38(12-14-39)23-4-2-22(3-5-23)36-29(41)37-33/h1-10,15,19-20,26H,11-14,16-18,33H2,(H2,36,37,41)/t26-,30-/m0/s1
• Code InChI: InChIKey=PROQIPRRNZUXQM-IZPLOLCNSA-N
• SMILES: C[C@]12CC[C@H]3c4ccc(O)cc4CC[C@H]3[C@H]1C[C@H](O)[C@@H]2O