7-O-(Triethylsilyl)-2’-O-tert-butyl(dimethyl)silyl-2-debenzoyl Paclitaxel

CAS : 162459-94-1

Ref. TR-T777830

Informations sur le produit

• Nom: 7-O-(Triethylsilyl)-2’-O-tert-butyl(dimethyl)silyl-2-debenzoyl Paclitaxel
• Synonymes: (alphaR,betaS)-beta-(Benzoylamino)-alpha-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11,12-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester

Description

Applications Paclitaxel (P132500) derivative. Intermediate in the preparation of benzoyl-substituted paclitaxel analogs.

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 978.32
• Formule: C₅₂H₇₅NO₁₃Si₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C52H75NO13Si2/c1-15-68(16-2,17-3)65-37-28-38-51(30-61-38,64-33(6)55)43-45(57)52(60)29-36(31(4)39(49(52,10)11)41(62-32(5)54)44(56)50(37,43)12)63-47(59)42(66-67(13,14)48(7,8)9)40(34-24-20-18-21-25-34)53-46(58)35-26-22-19-23-27-35/h18-27,36-38,40-43,45,57,60H,15-17,28-30H2,1-14H3,(H,53,58)/t36-,37-,38+,40-,41+,42+,43-,45-,50+,51-,52+/m0/s1
• Code InChI: InChIKey=OPYUSJFJMUNXDI-RURLCJGCSA-N
• SMILES: CC[Si](CC)(CC)O[C@H]1C[C@H]2OC[C@@]2(OC(C)=O)[C@H]2[C@H](O)[C@]3(O)C[C@H](OC(=O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](NC(=O)c4ccccc4)c4ccccc4)C(C)=C([C@@H](OC(C)=O)C(=O)[C@]12C)C3(C)C