Trilostane

CAS : 13647-35-3

Ref. TR-T795600

Informations sur le produit

• Nom: Trilostane
• Synonymes: Modrastane, Modrefen, Modrenal, Vetoryl, Win 24540,Desopan, Androst-2-ene-2-carbonitrile, 4,5-epoxy-3,17-dihydroxy-, (4alpha,5alpha,17beta)-, (4Alpha,5Alpha,17Beta)-3,17-Dihydroxy-4,5-Epoxyandrost-2-Ene-2-Carbonitrile, (4α,5α,17β)-4,5-Epoxy-3,17-dihydroxyandrost-2-ene-2-carbonitrile, 17-Hydroxy-3-Oxo-4,5-Epoxyandrostane-2-Carbonitrile, Androst-2-ene-2-carbonitrile, 4,5-epoxy-3,17-dihydroxy-, (4α,5α,17β)-, Desopan, Win 24540
• CAS: 13647-35-3

Description

Applications An inhibitor of steroid biosynthesis. Used as an adrenocortical suppressant. Used in the treatment of breast cancer.
References Komanicky, P., et al.: J. Clin. Endocrinol. Metab., 47, 1042 (1978), Mori, Y., et al., Chem. Pharm. Bull., 29, 2646 (1981), Williams, C.J., et al.: Cancer Treat. Rep., 71, 1197 (1987)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 329.43
• Formule: C₂₀H₂₇NO₃
• Couleur/Forme: White
• InChI: InChI=1S/C20H27NO3/c1-18-7-6-14-12(13(18)3-4-15(18)22)5-8-20-17(24-20)16(23)11(10-21)9-19(14,20)2/h12-15,17,22-23H,3-9H2,1-2H3/t12-,13-,14-,15-,17+,18-,19+,20+/m0/s1
• SMILES: C[C@]12CC[C@H]3[C@@H](CC[C@@]45O[C@@H]4C(O)=C(C#N)C[C@]35C)[C@@H]1CC[C@@H]2O