(R)-(+)-Verapamil Hydrochloride

CAS : 38176-02-2

Ref. TR-V124990

Informations sur le produit

• Nom: (R)-(+)-Verapamil Hydrochloride
• Synonymes: (aR)-a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)benzeneacetonitrile hydrochloride (1:1), (R)-a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)benzeneacetonitrile monohydrochloride, (+)-Verapamil hydrochloride, Dexverapamil monohydrochloride, LU 33925, NSC 632821, (2R)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile hydrochloride (1:1), (R)-Verapamil hydrochloride, Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, hydrochloride (1:1), (αR)-, Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, monohydrochloride, (R)-, Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, monohydrochloride, (αR)-, Lu 33925

Description

Applications (R)-(+)-Verapamil Hydrochloride and both of its isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Peroutka, S., et al.: J. Ann. Neurol, 23, 500 (1988); Eliason, J.F., et al.: Int. J. Cancer, 46, 113 (1990);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 491.06
• Formule: C₂₇H₃₈N₂O₄·ClH
• Couleur/Forme: Neat
• InChI: InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H/t27-;/m1./s1
• SMILES: COc1ccc(CCN(C)CCC[C@](C#N)(c2ccc(OC)c(OC)c2)C(C)C)cc1OC.Cl