Vernakalant Hydrochloride

CAS : 748810-28-8

Ref. TR-V128620

Informations sur le produit

• Nom: Vernakalant Hydrochloride
• Synonymes: (3R)- 1-[(1R,2R)-2-[2-(3,4-Dimethoxyphenyl)ethoxy]cyclohexyl]-3-pyrrolidinol Hydrochloride, (1R,2R)-2-((3R)-Hydroxypyrrolidinyl)-1-(3,4-dimethoxyphenethoxy)cyclohexane Monohydrochloride, (1R,2R)-2-((3R)-Hydroxypyrrolidinyl)-1-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexane Monohydrochloride, (3R)-1-[(1R,2R)-2-[2-(3,4-Dimethoxyphenyl)ethoxy]cyclohexyl]-3-pyrrolidinol Monohydrochloride, RSD 1235, (1R,2R)-2-((3R)-Hydroxypyrrolidinyl)-1-(3,4-dimethoxyphenethoxy)cyclohexane monohydrochloride, (1R,2R)-2-((3R)-Hydroxypyrrolidinyl)-1-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexane monohydrochloride, (3R)-1-[(1R,2R)-2-[2-(3,4-Dimethoxyphenyl)ethoxy]cyclohexyl]-3-pyrrolidinol monohydrochloride, 3-Pyrrolidinol, 1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]-, hydrochloride (1:1), (3R)-, 3-Pyrrolidinol, 1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]-, hydrochloride, (3R)-, Brinavess, Rsd-1235, Vernakalant hydrochloride
• CAS: 748810-28-8

Description

Applications Vernakalant Hydrochloride is a novel, relatively atrial-selective antiarrhythmic drug that effectively and rapidly terminates atrial fibrillation (AF).
References Mao, Z.L., et. al.: J. Clin. Pharmacol., 52, 1042 (2012); Mao, Z., et. al.: J. Pharmacokinet. Pharmacodynam., 38, 541 (2011)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 349.47 + (36.46)
• Formule: C₂₀H₃₁NO₄•HCl
• Couleur/Forme: Neat
• InChI: InChI=1S/C20H31NO4.ClH/c1-23-19-8-7-15(13-20(19)24-2)10-12-25-18-6-4-3-5-17(18)21-11-9-16(22)14-21;/h7-8,13,16-18,22H,3-6,9-12,14H2,1-2H3;1H/t16-,17-,18-;/m1./s1
• Code InChI: InChIKey=JMHYCBFEEFHTMK-IIUXMCBISA-N
• SMILES: COc1ccc(CCO[C@@H]2CCCC[C@H]2N2CC[C@@H](O)C2)cc1OC.Cl