Vildagliptin

CAS : 274901-16-5

Ref. TR-V305000

Informations sur le produit

• Nom: Vildagliptin
• Synonymes: (2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile, 2-Pyrrolidinecarbonitrile, 1-[[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-, (2S)- (9CI), (S)-1-[2-[(3-Hydroxyadamant-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile, DSP 7238, Equa, Galvus, LAF 237, NVP-LAF 237, (-)-(2S)-1-[[(3-Hydroxytricyclo[3.3.1.1[3,7]]dec-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile, (2S)-1-[2-[(3-Hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile, (2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.1^3,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile, (2S)-1-[N-(3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl)glycyl]pyrrolidine-2-carbonitrile, (3R)-3-amino-1-[6-(trifluoromethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one phosphate (1:1), 2-Pyrrolidinecarbonitrile, 1-[2-[(3-hydroxytricyclo[3.3.1.1^3,7]dec-1-yl)amino]acetyl]-, (2S)-, 2-Pyrrolidinecarbonitrile, 1-[[(3-hydroxytricyclo[3.3.1.1^3,7]dec-1-yl)amino]acetyl]-, (2S)-, Dsp 7238, Jalra, Laf 237, Nvp-Laf 237, Vidagliptin, Xiliarx

Description

Stability Hygroscopic
Applications Glyptins are class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.
References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 303.40
• Formule: C₁₇H₂₅N₃O₂
• Couleur/Forme: White
• InChI: InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14-,16?,17?/m0/s1
• SMILES: N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2