Vildagliptin Lactam

CAS : 1789703-36-1

Ref. TR-V305025

Informations sur le produit

• Nom: Vildagliptin Lactam
• Synonymes: Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-, Hexahydro-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)pyrrolo[1,2-a]pyrazine-1,4-dione, 2-(3-Hydroxyadamantan-1-yl)-6,7,8,8a-tetrahydro-3H-pyrrolo[1,2-a]pyrazine-1,4-dione
• CAS: 1789703-36-1

Description

Impurity Rac-Vildagliptin Impurity F
Applications Vildagliptin Lactam is an impurity of Vildagliptin (V305000). Glyptins are class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. ASide from there use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.
References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 304.38
• Formule: C₁₇H₂₄N₂O₃
• Couleur/Forme: Off-White
• InChI: InChI=1S/C17H24N2O3/c20-14-9-19(15(21)13-2-1-3-18(13)14)16-5-11-4-12(6-16)8-17(22,7-11)10-16/h11-13,22H,1-10H2
• Code InChI: InChIKey=XPKCFFJRILBMTQ-BQEHCZBJSA-N
• SMILES: O=C1CN([C@@]23C[C@@H]4C[C@@H](C[C@@](O)(C4)C2)C3)C(=O)C2CCCN12