Hydroxy Vildagliptin

Ref. TR-V305035

Informations sur le produit

• Nom: Hydroxy Vildagliptin
• Synonymes: (2S)-1-[2-[(3,5-dihydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile

Description

Applications Hydroxy Vildagliptin is an impurity of Vildagliptin (V305000). Vildagliptin is a DPP-​4 enzyme inhibitor, has anti-oxidant properties and used as an apoptotic agent on pancreatic cancer . Vildagliptin is used to treat type 2 diabetes mellitus (T2DM) and improve the endothelial function of patients.
References Amritha, C.A., et al.: J. Clin. Diagn. Res., 9, FC14 (2015); Cosenso-Martin, L.N., et al.: Diabetol. Metab. Syndr., 7, 70/1 (2015)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 319.40
• Formule: C₁₇H₂₅N₃O₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C17H25N3O3/c18-7-13-2-1-3-20(13)14(21)8-19-15-4-12-5-16(22,9-15)11-17(23,6-12)10-15/h12-13,19,22-23H,1-6,8-11H2/t12?,13-,15?,16?,17?/m0/s1
• SMILES: N#C[C@@H]1CCCN1C(=O)CN[C@@]12C[C@@H]3C[C@@](O)(C[C@@](O)(C3)C1)C2