Vinorelbine-d3 Bitartrate

CAS : 125317-39-7

Ref. TR-V315002

Informations sur le produit

• Nom: Vinorelbine-d3 Bitartrate
• Synonymes: 3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine-d3 Ditartrate, Nor-5'-anhydrovinblastine-d3 Ditartrate, Eunades-d3, Navelbine-d3, (3Ar,3A1R,4R,5S,5Ar,10Br)-Methyl 4-Acetoxy-3A-Ethyl-9-((2S,6S,8S)-4-Ethyl-8-(Methoxycarbonyl)-1,3,6,7,8,9-Hexahydro-2,6-Methanoazecino[4,3-B]Indol-8-Yl)-5-Hydroxy-8-Methoxy-6-Methyl-3A,3A1,4,5,5A,6,11, 3',4'-Didehydro-4'-Deoxy-C'-Norvincaleukoblastine, 3',4'-didehydro-4'-deoxy-c'-norvincaleukoblastine R-(R*,R*)-2-3-dihydroxybutanedioate (1:2) salt, 3′,4′-Didehydro-4′-deoxy-C′-norvincaleukoblastine tartrate, 5'-Noranhydrovinoblastine Tartrate, Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12R,19α)-, (2R,3R)-2,3-dihydroxybutanedioate (1:2) (salt), Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12β,19α)-, (2R,3R)-2,3-dihydroxybutanedioate (1:2) (salt), Bitartrate, Butanedioate(1:2), C'-norvincaleukoblastine,3',4'-didehydro-4'-dioxy-,(R-(R*,R*))-2,3-dihydroxy, C′-Norvincaleukoblastine, 3′,4′-didehydro-4′-deoxy-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:2) (salt), Kw 2307, Navelbine, Navelbine ditartrate, Navelbine tartrate, Nor-5′-anhydrovinblastine ditartrate, Nvb, Pacilitaxel, Vinorelbin, Vinorelbine bitartrate, Vinorelbine bitratrate, Vinorelbine ditartaric acid, Vinorelbine ditartrate salt, Vinorelbine tartarate, Vinorelbine tartrate, Vinorelbine tartrate usp standard, Vinorelbineditartrate salt hydrate, [R-(R*,R*)-2-3-dihydroxybutanedioate (1:2) salt], methyl (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(acetyloxy)-15-[(6R,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate, methyl (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(acetyloxy)-15-[(6R,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate 2,3-dihydroxybutanedioate (1:2), methyl (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(acetyloxy)-15-[(8S)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate 2,3-dihydroxybutanedioate (1:2)

Description

Stability Light Sensitive, Temperature Sensitive
Applications An antineoplastic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mathe, G., et al.: Cancer Letters, 27, 285 (1985), Levegue, D., et al.: Clin. Pharmacokinet., 31, 184 (1996), Curran, M.P., et al.: Drugs Aging., 19, 695 (2002),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 1082.12
• Formule: C₅₃H₆₃D₃N₄O₂₀
• Couleur/Forme: Neat
• InChI: InChI=1S/C45H54N4O8.C4H6O6/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7;5-1(3(7)8)2(6)4(9)10/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3;1-2,5-6H,(H,7,8)(H,9,10)/t28?,37-,38+,39+,42+,43+,44+,45-;/m0./s1/i6D3
• Code InChI: InChIKey=UUHYRRXICWUZHW-STRDHVDESA-N
• SMILES: O=C(O)C(O)C(O)C(=O)O.[2H]C([2H])([2H])OC(=O)[C@@]1(c2cc3c(cc2OC)N(C)[C@H]2[C@@](O)(C(=O)OC)[C@H](OC(C)=O)[C@]4(CC)C=CCN5CC[C@]32[C@@H]54)CC2C=C(CC)C[N@@](Cc3c1[nH]c1ccccc31)C2