XAV 939

CAS : 284028-89-3

Ref. TR-X744000

Informations sur le produit

• Nom: XAV 939
• Synonymes: NVP-XAV 939

Description

Applications A tankyrase (TNKS) inhibitor that antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. XAV 939 inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Huang, S. et al.: Nature, 461, 614 (2009); Wang, H. et al.: ACS Chem. Biol., 6, 192 (2011); Adles, M.E. et al.: Sci. Signal., 91, ec326 (2009);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 312.31
• Formule: C₁₄H₁₁F₃N₂OS
• Couleur/Forme: Neat
• InChI: InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
• Code InChI: InChIKey=KLGQSVMIPOVQAX-UHFFFAOYSA-N
• SMILES: O=c1nc(-c2ccc(C(F)(F)F)cc2)[nH]c2c1CSCC2