Informations sur le produit
Nom:Zoledronic acid
Produit contrôlé
Synonymes :
- Phosphonic acid
- [1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis- (9CI)
- (1-Hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid
- 1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene-1,1-bisphosphonic acid
- 2-(Imidazol-1-yl)-1-hydroxy-1,1'-ethylidenediphosphonic acid
- Aclasta
- BPH 91
- CGP 42446
- Orazol
- Reclast
- ZOL 446
- Zoledronate
- Zometa
- Phosphonic acid
- Voir plus de synonymes
Marque:TRC
Description :Stability extremely hygroscopic
Applications Zoledronic acid induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho.
References Jagdev, S., et al.: Br. J. Cancer, 84, 1126 (2001); Viereck, V., et al.: Biochem. Biophys. Res. Commun., 291, 680-686.Croucher. P., et al.: J. Bone Miner. Res., 2003, 18(3), 482-492.
Applications Zoledronic acid induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho.
References Jagdev, S., et al.: Br. J. Cancer, 84, 1126 (2001); Viereck, V., et al.: Biochem. Biophys. Res. Commun., 291, 680-686.Croucher. P., et al.: J. Bone Miner. Res., 2003, 18(3), 482-492.
Avis:Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Propriétés chimiques
Masse moléculaire :272.09
Formule :C5H10N2O7P2
Couleur/Forme :Neat
InChI :InChI=1S/C5H10N2O7P2/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14)
Code InChI :InChIKey=ZFXFMGARFHRTTO-UHFFFAOYSA-N
SMILES :COc1ccc(CC(=O)O)c(OC)c1