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Se termine le 31 déc.( plus que 7 jours )
GA-O-02
GA-O-02, an 18β-Glycyrrhetinic acid derivative, inhibits NO/cytokines and fights Gram-positive bacteria; potent anti-inflammatory/antimicrobial.Formule :C37H46ClNO6Couleur et forme :SolidMasse moléculaire :636.22GA-O-06
GA-O-06: 18β-Glycyrrhetinic acid derivative with powerful antimicrobial effects on Gram-positive bacteria and anti-inflammatory properties.Formule :C37H46FNO6Couleur et forme :SolidMasse moléculaire :619.76CFT8634
CAS :CFT8634 degrades BRD9, for synovial sarcoma and SMARCB1 tumor research, from patent WO2021178920A1.Formule :C37H45F3N6O5Couleur et forme :SolidMasse moléculaire :710.79VT02956
CAS :<p>VT02956 inhibits LATS1 (IC50: 0.76 nM) & LATS2 (0.52 nM), targets Hippo pathway, and hampers ER+ breast cancer growth.</p>Formule :C22H23N5OCouleur et forme :SolidMasse moléculaire :373.45PF-04979064
CAS :<p>PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM and 1.42 nM,respectively).</p>Formule :C24H26N6O3Degré de pureté :98.20% - ≥98%Couleur et forme :SolidMasse moléculaire :446.5KFU-127
KFU-127: broad-spectrum antimicrobial; targets bacterial/fungal biofilms; toxic to eukaryotic cells.Formule :C34H43BrN2O3Couleur et forme :SolidMasse moléculaire :607.62BAY-390
CAS :BAY-390, a selective TRPA1 inhibitor, crosses species, penetrates brains, with IC50s: 16-82 nM. Used in inflammation research.Formule :C13H15F4NOCouleur et forme :SolidMasse moléculaire :277.26MS47134
MS47134: potent MRGPRX4 agonist, EC50 = 149 nM, for pain/itch/hypersensitivity research.Formule :C22H29NO3Couleur et forme :SolidMasse moléculaire :355.47BI-2081
CAS :<p>BI-2081: GPR40 agonist, EC50=4nM, boosts insulin, lowers blood glucose, potential for type 2 diabetes research.</p>Formule :C32H35FO6Couleur et forme :SolidMasse moléculaire :534.62BI-2540
CAS :BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .Formule :C24H15ClF5NO5Couleur et forme :SolidMasse moléculaire :527.83AK-IN-1
CAS :AK-IN-1: competitive adenosine inhibitor, not ATP; inhibits AK 86-89% at 2-10 µM; promising for ischaemia, inflammation, seizure research.Formule :C22H21N3O4Couleur et forme :SolidMasse moléculaire :391.42DP00477
CAS :DP00477, a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), exhibits an inhibitory concentration (IC50) of 7.0 µM.Formule :C17H11ClF3N3OSCouleur et forme :SolidMasse moléculaire :397.8MK-3402
CAS :<p>MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .</p>Formule :C15H19N9O5S2Couleur et forme :SolidMasse moléculaire :469.50MPH-220
CAS :MPH-220: Oral myosin-2 inhibitor, induces muscle relaxation, useful for spasticity research.Formule :C20H21N3O3SCouleur et forme :SolidMasse moléculaire :383.46SDMA
CAS :<p>SDMA (Symmetric dimethylarginine) is the most potent endogenous inhibitor of nitric oxide synthase (NOS), with higher levels in patients with end-stage renal</p>Formule :C8H18N4O2Degré de pureté :95.74% - ≥98%Couleur et forme :SolidMasse moléculaire :202.25ccc_R08
CAS :<p>ccc_R08 is an HBV cccDNA inhibitor that reduces extracellular levels of HBV DNA, HBsAg, and HBeAg. ccc_R08 may be investigated in HBV infections.</p>Formule :C22H19ClO6Degré de pureté :99.45% - 99.86%Couleur et forme :SoildMasse moléculaire :414.84TBI-166
CAS :TBI-166, an oral riminophenazine, treats tuberculosis with fewer side effects than Clofazimine.Formule :C32H30F3N5O3Couleur et forme :SolidMasse moléculaire :589.61KM04416
CAS :<p>KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.</p>Formule :C12H11NO3SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :249.29STL1267
CAS :STL1267 is a REV-ERB agonist that crosses the blood-brain barrier and inhibits BMAL1 gene expression.Formule :C17H11ClN4ODegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :322.75BRD7586
CAS :BRD7586 is a cell-permeable small molecule inhibitor of SpCas9 that enhances SpCas9 specificity.Formule :C17H14ClN3O3S2Degré de pureté :97.70% - 99.03%Couleur et forme :SolidMasse moléculaire :407.89TIM-063
CAS :TIM-063: ATP-competitive CaMKKα/β inhibitor, cell-permeable, Ki: 0.35/0.2 μM, IC50: 0.63/0.96 μM.Formule :C18H9N3O4Couleur et forme :SolidMasse moléculaire :331.28BI-3231
CAS :<p>BI-3231 is a hydroxysteroid 17ß-dehydrogenase 13 HSD17B13 inhibitor that inhibits hHSD17B13 .BI-3231 can be used to study cirrhosis.</p>Formule :C16H14F2N4O3SDegré de pureté :98.2%Couleur et forme :SolidMasse moléculaire :380.37NP10679
CAS :NP10679 is a N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit that inhibits histamine H1, hERG channels, and CYPase.Formule :C23H26F3N3O3Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :449.47CZS-241
CZS-241: Oral PLK4 inhibitor (IC50=2.6 nM), less potent TRKA blocker (IC50=2.74 μM), triggers apoptosis and S/G2 arrest, anti-leukemia, safe for normal cells.Formule :C26H24ClF2N9OCouleur et forme :SolidMasse moléculaire :551.987-Hydroxy-4H-chromen-4-one
CAS :7-Hydroxy-4H-chromen-4-one (7-hydroxy-4-benzopyrone) is a Src kinase inhibitor (IC50 of <300 μM).Formule :C9H6O3Degré de pureté :97.65%Couleur et forme :SolidMasse moléculaire :162.14TH-Z145
CAS :<p>TH-Z145 is a potent FPPS inhibitor for the study of myeloma and lung cancer.</p>Formule :C16H28O7P2Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :394.34BAY-364
CAS :BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+Formule :C23H19N3O4Couleur et forme :SolidMasse moléculaire :401.41MRS4596
MRS4596: selective P2X4 blocker, IC50 1.38 μM, neuroprotective in stroke research.Formule :C21H14N5NaO3SCouleur et forme :SolidMasse moléculaire :439.42MRS4719
CAS :<p>MRS4719: potent P2X4 antagonist, IC50 0.503 μM. Reduces infarct, brain atrophy, Ca2+ influx. Used in ischemic stroke research.</p>Formule :C26H13N5O3S·C6H15NCouleur et forme :SolidMasse moléculaire :504.6SAHA-OH
CAS :SAHA-OH selectively inhibits HDAC6 (IC50 = 23 nM) with 10-47x preference over HDACs 1, 2, 3, 8, and reduces inflammation and macrophage apoptosis.Formule :C15H22N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :294.35Ph-HTBA
CAS :Ph-HTBA: high-affinity CaMKIIα modulator, brain-penetrant, Kd 757 nM, used in ischemia/neurodegeneration research.Formule :C19H18O3Couleur et forme :SolidMasse moléculaire :294.34DRP1i27
CAS :DRP1i27 inhibits human Drp1 at GTPase site, prevents mitochondrial fission, and shields cells from ischemia-reperfusion damage.Formule :C20H26N6OCouleur et forme :SolidMasse moléculaire :366.46DN-1289
<p>DN-1289: oral, BBB-penetrating, selectively inhibits DLK (IC50=17nM) & LZK (IC50=40nM), blocks p-c-Jun in mouse optic nerve crush.</p>Formule :C18H19F4N7O2Degré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :441.38LWG-301
LWG-301, a GLS1 allosteric inhibitor, IC50 7 nM, impedes glutamine metabolism and prompts apoptosis; shows antitumor effects.Formule :C28H38N8O3SCouleur et forme :SolidMasse moléculaire :566.72DS-9300
CAS :DS-9300, an orally administered potent and selective inhibitor of EP300/CBP HAT, exhibits a significant inhibitory activity with an IC50 value of 28 nM.Formule :C25H26F3N5O3Couleur et forme :SolidMasse moléculaire :501.50Lodenafil
CAS :Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)Formule :C23H32N6O5SDegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :504.6DDO3711
CAS :"DDO3711, a PHORC, links an ASK1 inhibitor to a PP5 activator, inhibiting ASK1 (IC50=164.1 nM), dephosphorylating p-ASK1, and showing anti-cancer potential."Formule :C42H41N9O6Couleur et forme :SolidMasse moléculaire :767.83BAY-805
CAS :BAY-805, a selective USP21 inhibitor, targets DUBs with high specificity.Formule :C24H28F3N5O2SDegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :507.57MK-8189
CAS :MK-8189 is a potent and selective pyrimidine PDE10A inhibitor, with excellent PDE (phosphodiesterase) selectivity for the treatment of schizophrenia.Formule :C19H22N6OSDegré de pureté :99.38% - 99.67%Couleur et forme :SolidMasse moléculaire :382.48(1R,2R)-MK-8189
CAS :(1R,2R)-MK-8189 is an isomer of MK-8189, a potent and selective pyrimidine PDE10A inhibitor.Formule :C19H22N6OSDegré de pureté :>99.99% - >99.99%Couleur et forme :SoildMasse moléculaire :382.48NX-2127
CAS :NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferativeFormule :C39H45N9O5Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :719.83TYA-018
CAS :<p>TYA-018 is an HDAC6 inhibitor with cardioprotective effects and is used in the study of dilated heart disease and heart failure.</p>Formule :C15H13ClF2N4O3S2Degré de pureté :98.64%Couleur et forme :SolidMasse moléculaire :434.87Goitrin
CAS :<p>Goitrin, from glucosinolate reactions, blocks thyroid peroxidase and iodine use, and fights H1N1.</p>Formule :C5H7NOSCouleur et forme :SolidMasse moléculaire :129.18Pulixin
CAS :Pulixin blocks FREP1 from P. falciparum, hinders parasite spread (EC50: 11µM), and stops its growth (EC50: 47nM).Formule :C14H11NO4Couleur et forme :SolidMasse moléculaire :257.24SG2057
CAS :<p>SG2057 (DRG16), a PBD dimer with pentyldioxy linkage, binds DNA minor groove, forms cross-links, and is a potent antitumor agent.</p>Formule :C33H36N4O6Couleur et forme :SolidMasse moléculaire :584.66CU-CPT-8m
CAS :CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)Formule :C14H12N4ODegré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :252.27PF-184
PF-184: potent IKK-2 inhibitor, selective over 30+ kinases; useful for asthma & COPD research. IC50: 37 nM.Formule :C32H32ClFN6O4Couleur et forme :SolidMasse moléculaire :619.09YLT-11
<p>YLT-11: Oral PLK4 inhibitor, Kd 5.2 nM; less effective on PLK1/2/3; inhibits cancer cell growth and induces G2/M arrest and apoptosis.</p>Formule :C24H24N6OCouleur et forme :SolidMasse moléculaire :412.49Erasin
Erasin is a STAT3 inhibitor induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and against Erlotinib-resistant cancer cells.Formule :C20H19N3O3Couleur et forme :SolidMasse moléculaire :349.38TPN729
CAS :TPN729, a PDE5 inhibitor, has an IC50 of 2.28 nM, used to research erectile dysfunction.Formule :C25H36N6O4SCouleur et forme :SolidMasse moléculaire :516.66
