CAS 100040-31-1

polipeptide inibitore gastrico umano

Descrizione:

Il polipeptide inibitore gastrico (GIP), noto anche come polipeptide insulinotropico dipendente dalla glucosio, è un ormone peptidico prodotto nelle cellule K del duodeno e del digiuno nel tratto gastrointestinale. Svolge un ruolo cruciale nel metabolismo del glucosio stimolando la secrezione di insulina dal pancreas in risposta all'assunzione di cibo, in particolare in presenza di glucosio e acidi grassi. Il GIP inibisce anche la secrezione di acido gastrico e la motilità gastrica, da cui il suo nome. La sostanza è composta da 42 aminoacidi ed è parte della famiglia delle incretine, che sono ormoni che migliorano il rilascio di insulina. L'azione del GIP è mediata attraverso recettori specifici sulle cellule beta pancreatiche e ha implicazioni nei disturbi metabolici come il diabete di tipo 2. Il numero CAS 100040-31-1 identifica univocamente questo peptide, facilitando il suo studio e la sua applicazione in contesti di ricerca e clinici. In generale, il GIP è significativo per comprendere l'interazione tra il sistema digestivo e la regolazione metabolica.

Formula: C₂₂₆H₃₃₈N₆₀O₆₆S

Sinonimi:

• H-Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH
• Gip (Human)

Gastric Inhibitory Polypeptide (human)

CAS: 100040-31-1

Gastric inhibitory polypeptide (GIP), an incretin, represents an essential regulator of insulin secretion and glucose homeostasis.

Formula: C₂₂₆H₃₃₈N₆₀O₆₆S

Purezza: 97.4%

Colore e forma: Whitish Powder

Peso molecolare: 4983.6

Ref: 01-4030658

gastric inhibitory polypeptide (human)-Asn-Ile-Thr-Gln-OH

CAS: 100040-31-1

Formula: C₂₂₆H₃₃₈N₆₀O₆₆S

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 4983.5293

Ref: IN-DA01EB06

GIP, human

CAS: 100040-31-1

Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.

Formula: C₂₂₆H₃₃₈N₆₀O₆₆S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 4983.6

Ref: TM-TP2018

GIP (Human)

CAS: 100040-31-1

GIP is a peptide that is produced by the cells of the small intestine. GIP has been shown to be an inhibitor of insulin secretion and, in turn, may help regulate glucose levels. It also regulates growth hormone release in response to food intake. GIP acts as a ligand for the receptor known as the “gastric inhibitory polypeptide receptor” which is found on pancreatic beta cells and duodenal L-cells. This protein has been shown to activate ion channels and regulate their activity. The GIP receptor is also expressed on certain types of cancer cells, including breast cancer and colorectal cancer. Antibodies have been generated against this protein for use in research tools such as Western blotting or immunohistochemistry.

Formula: C₂₂₆H₃₃₈N₆₀O₆₆S

Purezza: Min. 95%

Peso molecolare: 4,983.5 g/mol

Ref: 3D-PGR-4178-S

GIP (Human)

CAS: 100040-31-1

GIP (Gastric Inhibitory Polypeptide) is a peptide hormone that belongs to the family of incretin hormones. GIP has been shown to have an insulinotropic effect, which is mediated by its activation of glucose-dependent insulin release from pancreatic β-cells. It also has effects on lipid metabolism and plays a role in the regulation of food intake. GIP is produced by K cells in the ileum and colon and released into the bloodstream following food intake. The binding of GIP to its receptors leads to inhibition of gastric acid secretion, stimulation of gallbladder contraction, increased blood flow to the stomach, relaxation of pyloric sphincter muscles, and inhibition of gastric motility. This product is highly pure (> 98%) with no detectable endotoxin or other microbial contamination.

Formula: C₂₂₆H₃₃₈N₆₀O₆₆S

Purezza: Min. 95%

Peso molecolare: 4,983.5 g/mol

Ref: 3D-PGR-4178-V