CAS 101-31-5

(-)-Atropina

Descrizione:

(-)-Atropina è un alcaloide tropano derivato da piante della famiglia Solanaceae, in particolare dalla belladonna (Atropa belladonna) e da altre specie correlate. È caratterizzato dalla sua natura chirale, esistendo come un unico enantiomero, che è la forma (-), nota per la sua attività farmacologica. L'atropina è un'ammina terziaria con una formula molecolare di C17H23NO3 e un peso molecolare di circa 289,37 g/mol. È un solido cristallino incolore a giallo pallido che è solubile in solventi organici come alcol e cloroformio, ma ha una solubilità limitata in acqua. L'atropina agisce principalmente come un agente anticolinergico, bloccando l'azione dell'acetilcolina sui recettori muscarinici, il che porta a effetti come l'aumento della frequenza cardiaca, la dilatazione delle pupille e la riduzione delle secrezioni. Viene utilizzata clinicamente per trattare la bradicardia, come antidoto per avvelenamento da organofosfati e per indurre midriasi durante esami oftalmologici. A causa dei suoi potenti effetti, l'atropina deve essere usata con cautela, poiché può causare effetti collaterali come secchezza delle fauci, visione offuscata e tachicardia.

Formula: C₁₇H₂₃NO₃

InChI: InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16-/m1/s1

InChI key: InChIKey=RKUNBYITZUJHSG-FXUDXRNXSA-N

SMILES: O(C([C@H](CO)C1=CC=CC=C1)=O)[C@@H]2C[C@]3(N(C)[C@@](C2)(CC3)[H])[H]

Sinonimi:

• (-)-Atropine
• (1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate
• (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate
• (S)-(-)-Hyoscyamine
• (S)-Atropine
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-ol, (-)-tropate (ester)
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-yl (-)-tropate
• 1αH,5αH-Tropan-3α-ol, (-)-tropate (ester)
• 1αH,5αH-Tropan-3α-yl (-)-tropate
• 8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl 3-Hydroxy-2-Phenylpropanoate
• 8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate
• <span class="text-smallcaps">L</span>-Hyoscyamin
• <span class="text-smallcaps">L</span>-Hyoscyamine
• Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)-endo]-
• Cystospaz
• Daturine
• Duboisine
• Hiosciamina
• Hyoscyamin
• L-Hyoscyamin
• L-Hyoscyamine
• L-Hyoscyamine free base
• Tropic acid, 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-tropan-3α-yl ester, (-)-
• l-Atropine
• l-Tropine tropate

L-Hyoscyamine

CAS: 101-31-5

L-Hyoscyamine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₇H₂₃NO₃

Purezza: (HPLC) ≥90%

Colore e forma: Powder

Peso molecolare: 289.38

Ref: 11-0669

Hyoscine Hydrobromide EP impurity A

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Peso molecolare: 289.4

Ref: ST-EA-CP-H16001

Hyoscyamine

CAS: 101-31-5

Colore e forma: Neat

Ref: 61-FOR1699.00

(-)-Atropine

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 289.3694

Ref: IN-DA0003FJ

L-Hyoscyamine

CAS: 101-31-5

L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities.

Formula: C₁₇H₂₃NO₃

Purezza: 99.71% - 99.81%

Colore e forma: White Crystalline Powder

Peso molecolare: 289.37

Ref: TM-T0962

Scopolamine EP Impurity D (Hyoscine Hydrobromide EP Impurity A, Hyoscyamine, L-Atropine )

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Colore e forma: White To Off-White Solid

Peso molecolare: 289.38

Ref: 4Z-S-0121

Hyoscyamine

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Peso molecolare: 289.38

Ref: 7W-GY3235

Hyoscyamine

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Purezza: 95%~99%

Peso molecolare: 289.375

Ref: BP-BP0749

Hyoscyamine

Prodotto controllato

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Colore e forma: Neat

Peso molecolare: 289.37

Ref: 04-C14270500

Hyoscyamine

Prodotto controllato

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Colore e forma: Neat

Peso molecolare: 289.37

Ref: 86-MM1699.00

L-Atropine-d5

CAS: 101-31-5

Formula: C₁₇H₁₈D₅NO₃

Peso molecolare: 294.41

Ref: 4Z-A-151028

(-)-Hycosamine-d3

Prodotto controllato

CAS: 101-31-5

Applications (-)-Hycosamine-d3, is the labeled analogue of (-)-Hycosamine (H674300), a natural compound that has inhibitory activity against cholinesterases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brunhofer, G. et al.: Bioorg. Med. Chem., 20, 6669 (2012);

Formula: C₁₇D₃H₂₀NO₃

Colore e forma: Off-White

Peso molecolare: 292.39

Ref: TR-H674302

(-)-Hycosamine

Prodotto controllato

CAS: 101-31-5

Applications (-)-Hycosamine is a natural compound that has inhibitory activity against cholinesterases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brunhofer, G., et al.: Bioorg. Med. Chem., 20, 6669 (2012);

Formula: C₁₇H₂₃NO₃

Colore e forma: Neat

Peso molecolare: 289.37

Ref: TR-H674300

Scopolamine EP Impurity D (Hyoscine Hydrobromide EP Impurity A, Hyoscyamine, L-Atropine )

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Peso molecolare: 289.38

Ref: ST-EA-CP-S114019

Hyoscyamine

CAS: 101-31-5

Hyoscyamine is a tropane alkaloid that is found in plants of the Solanaceae family, such as henbane and jimson weed. It has been used for centuries to treat gastrointestinal disorders, spastic colon, urinary incontinence, and other conditions. The drug works by inhibiting the release of acetylcholine from nerve endings at synapses in the brain and along the gastrointestinal tract. Inhibition of acetylcholine release leads to an increase in parasympathetic activity which results in decreased motility and increased secretions. Hyoscyamine inhibits epoxidase activity, which may be associated with its anti-inflammatory properties. This drug also has transcriptional regulation effects on genes related to growth, development, and reproduction; it inhibits the synthesis of proteins that regulate cell growth and division. Scopolamine is a derivative of hyoscyamine that has been used as a sedative or preoperative medication to reduce saliva production and decrease bronchial

Formula: C₁₇H₂₃NO₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 289.37 g/mol

Ref: 3D-FH36337